Gluten Sensitivity, A Common Cause of Liver Dysfunction and Disease by Dr. O

Dr. Peter Osborne ( Dr. O) has graciously offered to supply monthly, up-to-date, helpful and important information about gluten and celiac issues. Dr. O is the Clinical Director of  Town Center Wellness and a Diplomate with the American Clinical Board of Nutrition.

More than 200 scientific studies have linked gluten sensitivity to liver disease.  In this review, the following liver conditions were linked to gluten intolerance:

  1. Reactive hepatitis ( coeliac hepatitis)
  2. Autoimmune liver disorders including – Autoimmune hepatitis, Autoimmune overlap syndrome,  Autoimmune (sclerosing) cholangitis, and Primary biliary cirrhosis
  3. Non alcoholic fatty liver disease
  4. Acute liver failure
  5. Cryptogenic cirrhosis
  6. Regenerative nodular hyperplasia
  7. Hepatocellular carcinoma (liver cancer)

“a wide spectrum of liver injuries in children and adults may be related to CD and in particular: (1) a mild parenchymal damage characterised by absence of any clinical sign or symptom suggesting a chronic liver disease and by non-specific histological changes reversible on a gluten-free diet; (2) a chronic inflammatory liver injury of autoimmune mechanism, including autoimmune hepatitis, primary sclerosing cholangitis and primary biliary cirrhosis, that may lead to fibrosis and cirrhosis, generally unaffected by gluten withdrawal and necessitating an immunosuppressive treatment; (3) a severe liver failure potentially treatable by a gluten-free diet. Such different types of liver injuries may represent a spectrum of a same disorder where individual factors, such as genetic predisposition, precocity and duration of exposure to gluten may influence the reversibility of liver damage.”


Indian J Pediatr 2006; 73 (9) : 809-811.

Liver disease can be fatal.  It has been well established that viral infection and alcohol can both damage the liver.  However; there are many who suffer with liver disease unrelated to either.  The cause for many of these conditions is unknown.

  • 500,000 gall bladder surgeries are performed in the U.S. annually.  Up to 40% of these surgeries have complications afterwards.
  • Non alcoholic fatty liver (NAFL) disease affects as many as 1/3 or U.S. adults.

The big question is why?  What is causing damage to the liver and gallbladder in so many individuals.  Is the answer surgery?  If gluten intolerance can cause all of the above conditions, shouldn’t we perform routine genetic screening for gluten sensitivity in those with liver disease of unknown origin before taking out their organs?

Now consider that liver disease can cause high cholesterol… Cholesterol medications can cause liver disease…Liver disease contributes to blood sugar abnormalities…contributes to fatigue…contributes to weight gain…contributes to fatty liver…

We can go on and on and on.  The point is, gluten intolerance can cause liver problems.  Most liver disease in the U.S. has no known cause.  It makes sense to investigate gluten as a causative factor.

In good health, Dr. Peter Osborne

Dr. Osborne is Diplomate with the American Clinical Board of Nutrition.  He specializes in the treatment of chronic disease and is the clinical director of Town Center Wellness in Sugar Land, TX.  He is the founder of, a website dedicated to teaching confused consumers about gluten and going gluten free.                     

From our home to yours, Tina Turbin
If you have any questions or suggestions just email me at info (at)

About Us

I'm a cookbook-collecting, recipe-developing paleo junkie, and I live in the kitchen. I'm hooked on farmers' markets, traveling, eating healthy, and hiking until my legs scream at me. There's nothing better than hanging out with family and good friends. I have fun and sleeping is just plain boring. Read more About Tina Turbin.

3 thoughts on “Gluten Sensitivity, A Common Cause of Liver Dysfunction and Disease by Dr. O

  1. Liver dysfunction and disease is really scary stuff! My family has had some of the symptoms in the past and have been in and out of hospitals. I feel it’s about time to test to see if we’re all celiac. Is being celiac hereditary? Can I pass it down to my children?

  2. Hello there, I was wondering if any of you has an experience or tryed this medicine. They make some wicked claims and I don’t know what to believe about it, I’ve watched the clips and i can say i’m a bit curious. Can someone tell if they had an experience with this “miracle soultion” they call MMS? I found it here but seems there is an entire comunity around it.

    I find myself in need, i’m a bit ill and my mother has cancer so i am willing to try anything that could heal this ilness. I would really appreciate your oppinions.

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